Contribution of cutaneous inputs from the hindpaw to the control of locomotion : 2 . Spinal cats
نویسنده
چکیده
The goal of these experiments was to define the contribution of hindpaw cutaneous inputs in the expression of spinal locomotion in cats. In 3 cats, some (n=1) or all (n=2) cutaneous nerves were cut bilaterally at ankle level before spinalisation. This denervation caused small deficits that were gradually compensated as reported in the companion paper (Bouyer and Rossignol, 2003a). After spinalisation, the completely denervated cats never recovered plantar foot placement or weight bearing of the hindquarters despite more than 35 days of treadmill training. While normal electromyographic rhythmic activity developed at the hip and knee, ankle flexors and extensors were abnormally co-activated during stance. In contrast, the partially denervated cat regained foot placement and weight support 15 days after spinalisation. However, after completing the denervation, foot placement and weight bearing were lost as in previous cats. In a fourth cat, spinalisation was performed prior to denervation and the cutaneous nerves were cut sequentially in the right hindlimb only. Rapid locomotor adaptation occurred after cutting the Deep Peroneal, Saphenous, and Sural nerves. Later, cutting the Superficial Peroneal nerve produced paw drag, which was compensated within 8 days. Upon cutting the last cutaneous nerve (Tibial), plantar foot placement was lost despite another 71 days of training. On the one hand, these experiments show that some cutaneous inputs are necessary for appropriate plantar foot placement and weight bearing of the hindquarters during spinal locomotion and, on the other hand, that locomotor compensation to partial cutaneous denervation after spinalisation reveals important adaptive capacities of the spinal cord.
منابع مشابه
Contribution of cutaneous inputs from the hindpaw to the control of locomotion. II. Spinal cats.
The goal of these experiments was to define the contribution of hindpaw cutaneous inputs in the expression of spinal locomotion in cats. In 3 cats, some (n = 1) or all (n = 2) cutaneous nerves were cut bilaterally at ankle level before spinalization. This denervation caused small deficits that were gradually compensated as reported in the companion study. After spinalization, the completely den...
متن کامل. Bouyer and S . Rossignol Control of Locomotion . I . Intact Cats Contribution of Cutaneous Inputs From the Hindpaw to the
متن کامل
Contribution of cutaneous inputs from the hindpaw to the control of locomotion. I. Intact cats.
The goal of this study was to evaluate the role of hindpaw cutaneous feedback in the control of locomotion, by cutting some (in one cat) or all (in 2 cats) cutaneous nerves bilaterally at ankle level. Kinematic and electromyographic (EMG) recordings were obtained before and for several weeks after denervation during level and incline (15 degrees up and down) treadmill walking. Ladder walking an...
متن کاملChanges in corticospinal efficacy contribute to the locomotor plasticity observed after unilateral cutaneous denervation of the hindpaw in the cat.
We used microwire electrodes chronically implanted into the hindlimb representation of the motor cortex as well as into the pyramidal tract to test the hypothesis that the corticospinal system contributes to the locomotor plasticity that is observed after cutaneous denervation of the cat hindpaw. A total of 23 electrodes implanted into the motor cortex in three cats trained to walk on a treadmi...
متن کاملAsymmetric changes in cutaneous reflexes after a partial spinal lesion and retention following spinalization during locomotion in the cat.
Locomotion involves dynamic interactions between the spinal cord, supraspinal signals, and peripheral sensory inputs. After incomplete spinal cord injury (SCI), interactions are disrupted, and remnant structures must optimize function to maximize locomotion. We investigated if cutaneous reflexes are altered following a unilateral partial spinal lesion and whether changes are retained within spi...
متن کامل